Psoriasis is a chronic inflammatory skin condition
where the skin cells shed in days instead of weeks. It is caused by combination
of a genetic trait that causes a quickened autoreactive immune response and
exposure to specific external factors. External factors such as
infections, physical trauma, stress, and certain drugs (lithium, antimalarials,
interferon, indomethacin, beta-blockers) can trigger a psoriasis
flare. Psoriasis affects people from young to old, with a peak incidence
around 22.5 years.
WHAT ARE THE SYMPTOMS OF PSORIASIS?
Psoriasis can present in different ways. It
very often affects the scalp, knees, elbows and lower back, but can also affect
the buttocks, palms, soles, armpits, ears, groin, and nails. The two most
common variants are chronic stable plaque psoriasis and acute guttate
psoriasis, with the former presenting as large red plaques with silvery scale
that can last for months, and the latter presenting as small pink or red scaly
bumps that erupt suddenly and can spontaneously resolve. 10-25% of patients
with psoriasis also have joint pains (psoriatic arthritis). The diagnosis of
psoriasis is often made clinically, but a skin biopsy may be done to confirm
the diagnosis.
WHAT ARE THE TREATMENTS FOR PSORIASIS?
There are many treatments for psoriasis,
including phototherapy, topical medications, and systemic medications.
Phototherapy involves exposing affected areas to artificial UVB light. Topical
medications include glucorticoids, vitamin
D derivatives, immunomodulators, and retinoids. Oral systemic medications such as
glucocorticoids, oral retinoids, and oral immunosuppressants are used as well, but require
bloodwork and close monitoring due to more serious potential side effects.
Biologic medications are injected at
specific weekly or monthly intervals and also require bloodwork and close
monitoring due to more serious potential side effects. Sometimes a combination
of therapies may be used.
Here at Florida Skin Center, we offer all
choices of treatment outlined above, but will tailor the treatment based on age of the patient,
site and extent of involvement, associated medical disorders, and previous
therapies. Please ask a provider about treatment options.
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